KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRB14
All Species:
17.58
Human Site:
S220
Identified Species:
42.96
UniProt:
Q14449
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14449
NP_004481.2
540
60988
S220
T
E
T
N
G
E
I
S
P
T
Q
I
L
Q
M
Chimpanzee
Pan troglodytes
XP_515864
540
61086
S220
T
E
T
N
G
E
I
S
P
T
Q
I
L
Q
M
Rhesus Macaque
Macaca mulatta
XP_001083447
775
86284
S457
W
C
Q
Q
S
N
G
S
Q
S
Q
L
L
Q
N
Dog
Lupus familis
XP_535936
453
51984
W164
K
E
Q
G
K
K
S
W
K
K
I
Y
F
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLM9
538
60554
S218
A
E
M
N
G
D
R
S
P
T
Q
I
L
Q
V
Rat
Rattus norvegicus
O88900
538
60574
S218
T
E
M
N
G
D
R
S
L
T
Q
I
P
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513329
596
67101
T277
S
E
T
N
G
E
I
T
H
T
Q
I
L
Q
M
Chicken
Gallus gallus
XP_422029
534
60990
K219
S
E
T
N
A
T
V
K
H
S
G
I
L
Q
M
Frog
Xenopus laevis
Q6DCV1
653
72662
N279
L
K
D
M
N
E
K
N
K
V
S
L
L
E
Q
Zebra Danio
Brachydanio rerio
Q6PFT9
646
70983
D276
L
K
D
M
K
E
K
D
K
E
Q
L
L
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
42
81.6
N.A.
86.1
85
N.A.
73.4
72.4
25.4
24.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
53.4
82.9
N.A.
91.8
91.3
N.A.
80.8
81.1
38.7
37.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
6.6
N.A.
66.6
60
N.A.
80
46.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
20
N.A.
80
73.3
N.A.
93.3
66.6
40
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
20
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
70
0
0
0
50
0
0
0
10
0
0
0
20
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
50
0
10
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
30
0
0
0
10
60
0
0
0
% I
% Lys:
10
20
0
0
20
10
20
10
30
10
0
0
0
0
0
% K
% Leu:
20
0
0
0
0
0
0
0
10
0
0
30
80
10
10
% L
% Met:
0
0
20
20
0
0
0
0
0
0
0
0
0
0
40
% M
% Asn:
0
0
0
60
10
10
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
30
0
0
0
10
0
0
% P
% Gln:
0
0
20
10
0
0
0
0
10
0
70
0
0
70
10
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
0
10
0
10
50
0
20
10
0
0
0
0
% S
% Thr:
30
0
40
0
0
10
0
10
0
50
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
20
% V
% Trp:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _